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產(chǎn)品英文名稱:Corning® stemgro® hMSC Medium
產(chǎn)品中文名稱:康寧人間充質(zhì)干細胞培養(yǎng)基
Corning® stemgro® 3335 hMSC Medium 的簡述
國內(nèi)外大量實驗表明,通過長期培養(yǎng)后獲得的骨髓間充質(zhì)干細胞具有非常廣泛的分化潛能。然而,常用培養(yǎng)基含有胎牛血清(FBS),增加了病原體、異種抗原、 批間不穩(wěn)定性。美國FDA正考慮禁止使用 FBS于細胞治療。為此,Corning®成功研制了stemgro®,一種無血清、無異種蛋白、化學成分明確的人間充質(zhì)干細胞培養(yǎng)基。Corning® Stemgro® 化學成分明確,設計用于人體骨髓間充質(zhì)干細胞的zui大程度擴增。Stemgro® 化學成分明確是由于它的成分既沒有化學合成,也沒有重組體生產(chǎn)。人間充質(zhì)干細胞培養(yǎng)基直接來源于非人體動物細胞,無異種蛋白質(zhì)。Stemgro®如果用于 一定組織細胞培養(yǎng)瓶中無需鋪板蛋白,可以節(jié)約鋪板材料和鋪板時間。
Corning 關(guān)于Stemgro®的測試的實驗結(jié)果表明,Stemgro/CellBIND 組合中培養(yǎng)的MSC 細胞具有*的細胞增殖能力,和*性的成倍增長時間。因此,在較短時間內(nèi),Stemgro 可以使研究者獲得更多的細胞,這對于臨床研究中而言,將是的選擇。
Corning® stemgro® 3335 hMSC Medium 的產(chǎn)品特性
1) 使用Stemgro® 培養(yǎng)基,配合使用CellBIND 培養(yǎng)板,可以不用諸如Fibronectin 等生物基質(zhì)膠進行鋪板操作,此款培養(yǎng)基也能使MSC 細胞很好的粘附并維持其日常增殖和生長。
2) 對比10%FBS 組和競爭對手的無血清培養(yǎng)基,Stemgro® 培養(yǎng)基能使細胞在較短時間內(nèi)獲得大量細胞,即具有優(yōu)異的擴增性。
3) Stemgro® 培養(yǎng)基能保證MSC 細胞的長梭形細胞形態(tài)(5 passages)、表面marker 特性、正常染色體組型以及細胞多能性。
4) 不同來源的MSC 均能在Stemgro® 培養(yǎng)基中保持相近的細胞增殖速率。
5) Stemgro® 培養(yǎng)基配合使用CellBIND 培養(yǎng)板,可以為高效擴增MSC 提供*無血清、無異源物質(zhì)、成分明確的環(huán)境和條件。
Corning® stemgro®人間充質(zhì)干細胞培養(yǎng)基英文描述
Human mesenchymal stem cells (hMSCs) hold promise for the treatment of a wide variety of diseases. Currently, fetal bovine serum (FBS) is added to the medium to achieve expansion of hMSCs. However, concerns have been raised over animal-born pathogens, immune reactions and lot-to-lot variations caused by the undefined nature of FBS. To address these issues, StemRD has developed Stemgro®, a chemically-defined, serum-free and xeno-free medium for the expansion of hMSCs.
The Stemgro® Chemically Defined MSC Medium (for simplicity, referred to as “Stemgro” in this document) has been designed for the maximum expansion of human mesenchymal stem cells (MSCs) derived from bone marrow, cord blood, or adipose tissue. Stemgro® is chemically defined as its components are either chemically synthesized, recombinantly produced and purified. It can be considered xeno-free as none of its ingredients are directly derived from non-human animals. Stemgro® further offers the convenience of no plate-coating if used with certain tissue culture vessels (see below), saving cost of coating materials and time needed for coating. This product has the potential of proliferation and differentiation of good, can differentiate into osteoblasts, adipocytes, chondrocytes.
華雅再生醫(yī)學工程技術(shù)有限公司是一家為干細胞研究員提供干細胞無血清培養(yǎng)基,支原體檢測試劑盒,心肌細胞株,人間充質(zhì)干細胞株,凍存管凍存盒,臍帶間充質(zhì)干細胞凍存袋,細胞實驗耗材等進口品牌高質(zhì)量產(chǎn)品。專注干細胞研究,關(guān)注干細胞治療產(chǎn)品,購買干細胞產(chǎn)品請到華雅再生醫(yī)學工程公司。